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1

Rapid, Simple, and Versatile Manufacturing of Recombinant Adeno-Associated Viral Vectors at Scale

Lock, Martin, Alvira, Mauricio, Vandenberghe, Luk H., Samanta, Arabinda, Toelen, Jaan, Debyser, Zeger, Wilson, James M.

Journal:

Human Gene Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 830 KB

english, 2010

2

Maternal administration of betamethasone inhibits proliferation induced by fetal tracheal occlusion in the nitrofen rat model for congenital diaphragmatic hernia: a placebo-controlled study

Steffi Mayer, Philipp Klaritsch, Lourenço Sbragia, Jaan Toelen, Holger Till, Jan A. Deprest

Journal:

Pediatric Surgery International

Année:

2008

Langue:

english

Fichier:

PDF, 340 KB

english, 2008

3

Serum procalcitonin is not an early marker of pulmonary exacerbation in children with cystic fibrosis

Jacoba Johanna Louw, Jaan Toelen, Marijke Proesmans, François Vermeulen, Jaak Billen, Kris de Boeck

Journal:

European Journal of Pediatrics

Année:

2012

Langue:

english

Fichier:

PDF, 88 KB

english, 2012

4

Highly Efficient Multicistronic Lentiviral Vectors with Peptide 2A Sequences

Ibrahimi, Abdelilah, Velde, Greetje Vande, Reumers, Veerle, Toelen, Jaan, Thiry, Irina, Vandeputte, Caroline, Vets, Sofie, Deroose, Christophe, Bormans, Guy, Baekelandt, Veerle

Journal:

Human Gene Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 674 KB

english, 2009

5

Long term pulmonary gene therapy with a lentiviral vector in a fetal rat model

Jaan Toelen, Gijsbers Rik, Lourenço Sbragia, Deroose Christophe, Zeger Debyser, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2006

Langue:

english

Fichier:

PDF, 55 KB

english, 2006

6

Transduction of human pulmonary epithelial cell lines with a lentiviral vector

Jaan Toelen, Lourenço Sbragia, Rik Gijsbers, Desmet Sara, Xenia Roubliova, Zeger Debyser, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2006

Langue:

english

Fichier:

PDF, 58 KB

english, 2006

7

Feasibility and efficacy of different tracheal occlusion methods in a fetal rat model

Lourenço Sbragia, Jaan Toelen, Rik Gijsbers, Paul Lewi, Debyser Zeger, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2006

Langue:

english

Fichier:

PDF, 65 KB

english, 2006

8

Fetal gene transfer with lentiviral vectors: long-term in vivo follow-up evaluation in a rat model

Jaan Toelen, Christophe M. Deroose, Rik Gijsbers, Veerle Reumers, Lourenço N. Sbragia, Sofie Vets, Satish K. Chitneni, Guy Bormans, Luc Mortelmans, Jan A. Deprest, Zeger Debyser

Journal:

American Journal of Obstetrics and Gynecology

Année:

2007

Langue:

english

Fichier:

PDF, 724 KB

english, 2007

9

550: Placebo controlled study on effect of intratracheal instillation of albumin prior to tracheal occlusion in nitrofen rats with CDH

Philipp Klaritsch, Lourenço Sbragia, Jaan Toelen, Steffi Mayer, Xenia Roubliova, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2007

Langue:

english

Fichier:

PDF, 50 KB

english, 2007

10

584: Ex-vivo assessment of the effect of airway epithelial barrier disruption on transduction efficiency of a lentiviral vector in fetal rat tracheas

Sofie Vets, Jaan Toelen, Marianne Carlon, Rik Gijsbers, Lourenço Sbragia, Zeger Debyser, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2007

Langue:

english

Fichier:

PDF, 87 KB

english, 2007

11

241: Effects of tracheal occlusion and albumin on proliferation in fetal rats with nitrofen induced congenital diaphragmatic hernia – A placebo controlled molecular study

Philipp Klaritsch, Steffi Mayer, Lourenco Sbragia, Jaan Toelen, Zeger Debyser, Martin Haeusler, Xenia Roubliova, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2008

Langue:

english

Fichier:

PDF, 98 KB

english, 2008

12

439: Intra-amniotic VEGF administration in fetal rats with nitrofen induced lung hypoplasia – A placebo controlled study

Philipp Klaritsch, Steffi Mayer, Jaan Toelen, Lourenco Sbragia, Veronika Beck, Scott Petersen, Peter Carmeliet, Zeger Debyser, Uwe Lang, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2008

Langue:

english

Fichier:

PDF, 143 KB

english, 2008

13

653: Evaluation of different screening models for optimal pulmonary transduction with lentiviral vectors

Marianne Carlon, Jaan Toelen, Steffi Mayer, Rik Gijsbers, Lourenco Sbragia, Jan Deprest, Zeger Debyser

Journal:

American Journal of Obstetrics and Gynecology

Année:

2008

Langue:

english

Fichier:

PDF, 189 KB

english, 2008

14

35: Maternal administration of betamethasone inhibits pulmonary proliferation but stimulates maturation after fetal tracheal occlusion in the nitrofen rat model - A placebo controlled study

Steffi Mayer, Philipp Klaritsch, Lourenço Sbragia, Jaan Toelen, Holger Till, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2008

Langue:

english

Fichier:

PDF, 115 KB

english, 2008

15

721: Combined non-invasive bioluminiscence and magnetic resonance imaging improves detection after pulmonary gene transfer in a fetal mouse model

Marianne Carlon, Jaan Toelen, Uwe Himmelreich, Zeger Debyser, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2009

Langue:

english

Fichier:

PDF, 188 KB

english, 2009

16

722: Fetal tracheal injection technique to target the fetal mouse lung

Jaan Toelen, Marianne Carlon, Steffi Mayer, Lourenco Sbragia, Zeger Debyser, Jan Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2009

Langue:

english

Fichier:

PDF, 188 KB

english, 2009

17

Albumin as an adjunct to tracheal occlusion in fetal rats with congenital diaphragmatic hernia: a placebo-controlled study

Philipp Klaritsch, Steffi Mayer, Lourenço Sbragia, Jaan Toelen, Xenia Roubliova, Paul Lewi, Jan A. Deprest

Journal:

American Journal of Obstetrics and Gynecology

Année:

2010

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2010

18

414: Routine clonal expansion of mesenchymal stem cells derived from amniotic fluid

Silvia Zia, Jan Deprest, Marina Mori da Cunha, Philip DeKoninck, Jaan Toelen, Paolo De Coppi

Journal:

American Journal of Obstetrics and Gynecology

Année:

2012

Langue:

english

Fichier:

PDF, 274 KB

english, 2012

19

415: Amniotic fluid derived mesenchymal stem cells engraft in the cardiopulmonary system after early systemic injection in newborn mice

Marina Mori da Cunha, Jan Deprest, Silvia Zia, Philip DeKoninck, Jute Richter, Jaan Toelen

Journal:

American Journal of Obstetrics and Gynecology

Année:

2012

Langue:

english

Fichier:

PDF, 57 KB

english, 2012

20

416: Amniotic fluid derived mesenchymal stem cells as delivery vehicles for therapeutic factors

Jaan Toelen, Jan Deprest, Silvia Zia, Marina Mori da Cunha, Marianne Carlon, Philip DeKoninck, Zeger Debyser

Journal:

American Journal of Obstetrics and Gynecology

Année:

2012

Langue:

english

Fichier:

PDF, 57 KB

english, 2012

21

421: Isolation and expansion of rabbit amniotic fluid stem cells (AFS) for in-vivo stem cell therapy

DeKoninck, Philip, Deprest, Jan, Toelen, Jaan, Silvia, Zia, Albersen, Maarten, Mori, Bia, Lories, Rik, De Coppi, Paulo

Journal:

American Journal of Obstetrics and Gynecology

Année:

2013

Langue:

english

Fichier:

PDF, 150 KB

english, 2013

22

Granulomatous inflammation in cartilage-hair hypoplasia: Risks and benefits of anti–TNF-α mAbs

Moshous, Despina, Meyts, Isabelle, Fraitag, Sylvie, Janssen, Carl E.I., Debré, Marianne, Suarez, Felipe, Toelen, Jaan, De Boeck, Kris, Roskams, Tania, Deschildre, Antoine, Picard, Capucine, Bodemer, C

Journal:

Journal of Allergy and Clinical Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 618 KB

english, 2011

23

Fetoscopic surgery: Encouraged by clinical experience and boosted by instrument innovation

Jan Deprest, Jacques Jani, Liesbeth Lewi, Nicole Ochsenbein-Kölble, Mieke Cannie, Elisa Doné, Xenia Roubliova, Tim Van Mieghem, Anne Debeer, Frederik Debuck, Laurenço Sbragia, Jaan Toelen, Roland Devl

Journal:

Seminars in Fetal and Neonatal Medicine

Année:

2006

Langue:

english

Fichier:

PDF, 784 KB

english, 2006

24

Long term respiratory outcomes of congenital diaphragmatic hernia, esophageal atresia, and cardiovascular anomalies

Christophe Delacourt, Alice Hadchouel, Jaan Toelen, Maissa Rayyan, Jacques de Blic, Jan Deprest

Journal:

Seminars in Fetal and Neonatal Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 914 KB

english, 2012

25

Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity

Verschuere, Tina, Toelen, Jaan, Maes, Wim, Poirier, Françoise, Boon, Louis, Tousseyn, Thomas, Mathivet, Thomas, Gerhardt, Holger, Mathieu, Veronique, Kiss, Robert, Lefranc, Florence, Van Gool, Stefaan

Journal:

International Journal of Cancer

Année:

2014

Langue:

english

Fichier:

PDF, 729 KB

english, 2014

26

A pictorial essay on fetal rabbit anatomy using micro-ultrasound and magnetic resonance imaging

DeKoninck, Philip, Endo, Masayuki, Sandaite, Inga, Richter, Jute, De Catte, Luc, Van Calster, Ben, Toelen, Jaan, Himmelreich, Uwe, Claus, Filip, Deprest, Jan

Journal:

Prenatal Diagnosis

Année:

2014

Langue:

english

Fichier:

PDF, 4.24 MB

english, 2014

27

Routine isolation and expansion late mid trimester amniotic fluid derived mesenchymal stem cells in a cohort of fetuses with congenital diaphragmatic hernia

DeKoninck, Philip, Toelen, Jaan, Zia, Silvia, Albersen, Maarten, Lories, Rik, Coppi, Paolo De, Deprest, Jan

Journal:

European Journal of Obstetrics & Gynecology and Reproductive Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2014

28

A 6-Year-Old Girl with a Lingual Ulcer

Raaijmakers, Anke, Toelen, Jaan

Journal:

The Journal of Pediatrics

Année:

2013

Langue:

english

Fichier:

PDF, 259 KB

english, 2013

29

763: The use of human amniotic fluid stem cells as an adjunct to promote pulmonary development: RCT in a rabbit model for congenital diaphragmatic hernia

DeKoninck, Philip, Deprest, Jan, Toelen, Jaan, Russo, Francesca, Richter, Jute, Vandersloten, Pieter-Jan, Carter, Shea, Verbeken, Erik, De Coppi, Paolo

Journal:

American Journal of Obstetrics and Gynecology

Année:

2014

Langue:

english

Fichier:

PDF, 263 KB

english, 2014

30

Chronische abdominale pijn bij een adolescent

Mw. dr. Lien Lepere,dhr. Prof.dr. Jaan Toelen

Journal:

Tijdschrift voor Kindergeneeskunde

Année:

2014

Langue:

dutch

Fichier:

PDF, 488 KB

dutch, 2014

31

A Ray of Light for Fetal Therapy

Toelen, Jaan, Deprest, Jan

Journal:

Human Gene Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 51 KB

english, 2010

32

Immunological Ignorance Allows Long-Term Gene Expression After Perinatal Recombinant Adeno-Associated Virus-Mediated Gene Transfer to Murine Airways

Carlon, Marianne S., Vidović, Dragana, Dooley, James, da Cunha, Marina Mori, Maris, Michael, Lampi, Youlia, Toelen, Jaan, Van den Haute, Chris, Baekelandt, Veerle, Deprest, Jan, Verbeken, Erik, Liston

Journal:

Human Gene Therapy

Année:

2014

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2014

33

Routine clonal expansion of mesenchymal stem cells derived from amniotic fluid for perinatal applications

Zia, Silvia, Toelen, Jaan, da Cunha, Marina Mori, DeKoninck, Philip, de Coppi, Paolo, Deprest, Jan

Journal:

Prenatal Diagnosis

Année:

2013

Langue:

english

Fichier:

PDF, 4.49 MB

english, 2013

34

338: Proton-pump inhibitor omeprazole attenuates hyperoxia induced lung injury

Richter, Jute, Jimenez, Julio, Nagatomo, Taro, Vanoirbeek, Jeroen, Deprest, Jan, Toelen, Jaan

Journal:

American Journal of Obstetrics and Gynecology

Année:

2015

Langue:

english

Fichier:

PDF, 279 KB

english, 2015

35

337: Transplacental administration of rosiglitazone attenuates hyperoxic lung injury in a preterm rabbit model

Richter, Jute, Deprest, Jan, Nagatomo, Taro, Jimenez, Julio, Vanoirbeek, Jeroen, Toelen, Jaan

Journal:

American Journal of Obstetrics and Gynecology

Année:

2015

Langue:

english

Fichier:

PDF, 390 KB

english, 2015

36

547: Amniotic fluid stem cells accelerate muscle regeneration

Zia, Silvia, Di Filippo, Ester Sara, Quattrocelli, Mattia, Lewi, Liesbeth, Sindhwani, Nikhil, Sampaolesi, Maurilio, Deprest, Jan, Toelen, Jaan

Journal:

American Journal of Obstetrics and Gynecology

Année:

2015

Langue:

english

Fichier:

PDF, 401 KB

english, 2015

37

317: Intratracheal delivery of amniotic fluid derived stem cells (AFSc) in perfluorcarbon as compared to tracheal occlusion (TO)

Russo, Francesca, Zia, Silvia, Jimenez, Julio, Eastwood, Patrice, Toelen, Jaan, Deprest, Jan

Journal:

American Journal of Obstetrics and Gynecology

Année:

2015

Langue:

english

Fichier:

PDF, 238 KB

english, 2015

38

63: Transplacental sildenafil rescues vascular and airway morphometry in the rabbit model of congenital diaphragmatic hernia

Russo, Francesca, MiYague, Andre Hadyme, Eastwood, Patrice, DeKoninck, Philip, Velde, Greetje Vande, Allegaert, Karel, Himmelreich, Uwe, Toelen, Jaan, Vergani, Patrizia, Deprest, Jan

Journal:

American Journal of Obstetrics and Gynecology

Année:

2015

Langue:

english

Fichier:

PDF, 321 KB

english, 2015

39

Safe and effective cryopreservation methods for long-term storage of human-amniotic-fluid-derived stem cells

Hennes, Aurélie, Gucciardo, Léonardo, Zia, Silvia, Lesage, Flore, Lefèvre, Nicolas, Lewi, Liesbeth, Vorsselmans, Annick, Cos, Teresa, Lories, Rik, Deprest, Jan, Toelen, Jaan

Journal:

Prenatal Diagnosis

Année:

2015

Langue:

english

Fichier:

PDF, 572 KB

english, 2015

40

Van Wyk and Grumbach syndrome: an unusual form of precocious puberty

Christens, Anja, Sevenants, Lieve, Toelen, Jaan, Bullens, Dominique, Casteels, Kristina

Journal:

Gynecological Endocrinology

Année:

2014

Langue:

english

Fichier:

PDF, 362 KB

english, 2014

41

FK506 reduces neuroinflammation and dopaminergic neurodegeneration in an α-synuclein-based rat model for Parkinson's disease

Van der Perren, Anke, Macchi, Francesca, Toelen, Jaan, Carlon, Marianne S., Maris, Michael, de Loor, Henriette, Kuypers, Dirk R.J., Gijsbers, Rik, Van den Haute, Chris, Debyser, Zeger, Baekelandt, Vee

Journal:

Neurobiology of Aging

Année:

2015

Langue:

english

Fichier:

PDF, 3.16 MB

english, 2015

42

Longitudinal follow-up and characterization of a robust rat model for Parkinson's disease based on overexpression of alpha-synuclein with adeno-associated viral vectors

Van der Perren, Anke, Toelen, Jaan, Casteels, Cindy, Macchi, Francesca, Van Rompuy, Anne-Sophie, Sarre, Sophie, Casadei, Nicolas, Nuber, Silke, Himmelreich, Uwe, Osorio Garcia, Maria Isabel, Michotte,

Journal:

Neurobiology of Aging

Année:

2015

Langue:

english

Fichier:

PDF, 3.56 MB

english, 2015

43

Medical and Regenerative Solutions for Congenital Diaphragmatic Hernia: A Perinatal Perspective

Deprest, Jan, Gucciardo, Leonardo, Eastwood, Patrice, Zia, Silvia, Jimenez, Julio, Russo, Francesca, Lesage, Flore, Lewi, Liesbeth, Sampaolesi, Maurilio, Toelen, Jaan

Journal:

European Journal of Pediatric Surgery

Année:

2014

Langue:

english

Fichier:

PDF, 273 KB

english, 2014

44

Galectin-1 in Melanoma Biology and Related Neo-Angiogenesis Processes

Mathieu, Véronique, de Lassalle, Elisabeth Martin, Toelen, Jaan, Mohr, Thomas, Bellahcène, Akeila, Van Goietsenoven, Gwendoline, Verschuere, Tina, Bouzin, Caroline, Debyser, Zeger, De Vleeschouwer, St

Journal:

The Journal of Investigative Dermatology

Année:

2012

Langue:

english

Fichier:

PDF, 8.96 MB

english, 2012

45

The Effect of Transplacental Administration of Glucagon-Like Peptide-1 on Fetal Lung Development in the Rabbit Model of Congenital Diaphragmatic Hernia

Eastwood, Mary Patrice, Kampmeijer, Anouck, Jimenez, Julio, Zia, Silvia, Vanbree, Rieta, Verbist, Godelieve, Toelen, Jaan, Deprest, Jan A.

Journal:

Fetal Diagnosis and Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 327 KB

english, 2015

46

Efficient Gene Transfer Into the Mouse Lung by Fetal Intratracheal Injection of rAAV2/6.2

Carlon, Marianne, Toelen, Jaan, Van der Perren, Anke, Vandenberghe, Luk H, Reumers, Veerle, Sbragia, Lourenço, Gijsbers, Rik, Baekelandt, Veerle, Himmelreich, Uwe, Wilson, James M, Deprest, Jan, Debys

Journal:

Molecular Therapy

Année:

2010

Langue:

english

Fichier:

PDF, 787 KB

english, 2010

47

Prenatal interventions to prevent bronchopulmonary dysplasia in animal models: a systematic review

Jimenez, Julio, Richter, Jute, Toelen, Jaan, Deprest, Jan

Journal:

Journal of Maternal-Fetal and Neonatal Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 519 KB

english, 2015

48

Caffeine Prevents Hyperoxia-Induced Functional and Structural Lung Damage in Preterm Rabbits

Nagatomo, Taro, Jim�nez, Julio, Richter, Jute, De Baere, Siegrid, Vanoirbeek, Jeroen, Naulaers, Gunnar, Allegaert, Karel, Croubels, Siska, Deprest, Jan A., Toelen, Jaan

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2016

49

A Swollen, Red Areola in a Young Boy

Van Nieuwenhove, Erika, Toelen, Jaan, Casteels, Kristina

Journal:

JAMA Pediatrics

Année:

2016

Langue:

english

Fichier:

PDF, 209 KB

english, 2016

50

State-of-the-Art Lentiviral Vectors for Research Use: Risk Assessment and Biosafety Recommendations

Pauwels, Katia, Gijsbers, Rik, Toelen, Jaan, Schambach, Axel, Willard-Gallo, Karen, Verheust, Celine, Debyser, Zeger, Herman, Philippe

Journal:

Current Gene Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 278 KB

english, 2009